Date of Award

1-1-2009

Document Type

Dissertation

Degree Name

Ph.D.

Department

Psychology

First Advisor

Cynthia A. McRae

Keywords

Behavioral Medicine, Deep Brain Stimulation, Movement Disorders, Parkinson Disease, Psychology, Quality of Life

Abstract

Quality of Life (QOL) in Parkinson's disease (PD) patients after Deep Brain Stimulation (DBS) neurosurgery generally improves between 3 to 24 months post-operatively. However, QOL beyond 2 year follow-up is generally unknown. This study examined the QOL in 16 advanced PD patients who received DBS at an average of 7.5 year follow-up with the Parkinson's Disease Questionnaire (PDQ-39). Participants had an average Disease Duration of 20.57 years (SD 5.7) and a mean Age of 63.50 (SD 8.05). Linear regression analyses suggested a constellation of changes involving Time, Age, and Disease Duration. As Time progressed since DBS intervention, the PDQ-39 Cognitions subscale worsened (p < .05). Increasing Age was associated with improvement in Stigma-related QOL (p < .01). Rising Disease Duration correlated with improvements in three PDQ-39 subscales: (a) Stigma (p < .01), (b) Emotional Well-Being (p < .01), and (c) Social Support (p < .05). Findings suggested the need to further explore the domains and dimensions of QOL change post-DBS intervention, as well as other methods to measure the depth and breadth of QOL in DBS recipients.

Provenance

Recieved from ProQuest

Rights holder

Karl Chiang

File size

171 p.

File format

application/pdf

Language

en

Discipline

Clinical psychology, Mental health, Behavioral sciences

Share

COinS