Date of Award

1-1-2019

Document Type

Thesis

Degree Name

M.S.

Department

Mechanical Engineering

First Advisor

Chadd W. Clary

Keywords

Fixation Strength, Knee Balance Assessment, Lipid Contamination, Lipid Marrow Infiltration, Total Knee Arthroplasty

Abstract

Despite recent advancements in implant design and cement technique, aseptic tibial

loosening remains the primary cause of revision after cemented total knee arthroplasty

(TKA) [1]. While the mechanisms of tibial loosening are multifactorial, previous research

has shown that third-generation cement techniques, including the use of jet lavage and

cement pressurization, can reduce contamination of the implant surface by lipids

endogenous to the surrounding cancellous bone and thereby enhance fixation strength

between the implant and bone [2]. The purpose of this thesis is to understand the role

contaminating lipids play in the mechanism of aseptic loosening and to perform a

cadaveric study on modern commercially available TKA systems to evaluate their ability

to mitigate the risks of poor fixation. The results from this study indicate that tibial

components with no cement mantle around the cone or keel structure provide greater

fixation and enhanced robustness to intraoperative knee balance assessment

manipulations.

Provenance

Recieved from ProQuest

Rights holder

Yashar Ali Behnam

File size

73 p.

File format

application/pdf

Language

en

Discipline

Bioengineering

Available for download on Sunday, August 01, 2021

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