Date of Award

1-1-2019

Document Type

Masters Thesis

Degree Name

M.S.

Organizational Unit

Daniel Felix Ritchie School of Engineering and Computer Science, Mechanical and Materials Engineering

First Advisor

Chadd W. Clary, Ph.D.

Keywords

Fixation strength, Knee balance assessment, Lipid contamination, Lipid marrow infiltration, Total knee arthroplasty

Abstract

Despite recent advancements in implant design and cement technique, aseptic tibial loosening remains the primary cause of revision after cemented total knee arthroplasty (TKA) [1]. While the mechanisms of tibial loosening are multifactorial, previous research has shown that third-generation cement techniques, including the use of jet lavage and cement pressurization, can reduce contamination of the implant surface by lipids endogenous to the surrounding cancellous bone and thereby enhance fixation strength between the implant and bone [2]. The purpose of this thesis is to understand the role contaminating lipids play in the mechanism of aseptic loosening and to perform a cadaveric study on modern commercially available TKA systems to evaluate their ability to mitigate the risks of poor fixation. The results from this study indicate that tibial components with no cement mantle around the cone or keel structure provide greater fixation and enhanced robustness to intraoperative knee balance assessment manipulations.

Publication Statement

Copyright is held by the author. User is responsible for all copyright compliance.

Rights Holder

Yashar Ali Behnam

Provenance

Received from ProQuest

File Format

application/pdf

Language

en

File Size

73 p.

Discipline

Bioengineering

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