Creating Custom Foldit Puzzles for Teaching Biochemistry

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College of Natual Science and Mathematics, Chemistry and Biochemistry


Biochemistry, Puzzles, Web-based learning


The computer game Foldit is currently widely used as a biology and biochemistry teaching aid. Herein, we introduce a new feature of Foldit called “custom contests” that allows educators to create puzzles that fit their curriculum. The effectiveness of the custom contests is demonstrated by the use of five distinct custom contests in an upper‐level biochemistry class. The new custom contest feature can be implemented in classes ranging from middle school to graduate school to enable educators to best complement their current curriculum. © 2019 International Union of Biochemistry and Molecular Biology, 47(2): 133–139, 2019.

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