Publication Date
2022
Document Type
Article
Organizational Units
Sturm College of Law
Keywords
Dose optimization, Resource allocation, Medicine, Public Health, Pharmacology, Drugs
Abstract
Objective: A deep understanding of the relationship between a scarce drug's dose and clinical response is necessary to appropriately distribute a supply-constrained drug along these lines.
Summary of key data: The vast majority of drug development and repurposing during the COVID-19 pandemic – an event that has made clear the ever-present scarcity in health care systems –has been ignorant of scarcity and dose optimisation's ability to help address it.
Conclusions: Future pandemic clinical trials systems should obtain dose optimisation data, as these appear necessary to enable appropriate scarce resource allocation according to societal values.
Copyright Date
2022
Copyright Statement / License for Reuse
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Publication Statement
Copyright is held by the author. User is responsible for all copyright compliance.
File Format
application/pdf
Publication Title
BMJ Open
Recommended Citation
Garth Strohbehn, Govind Persad, William F. Parker & Srinivas Murthy, Dose Optimisation and Scarce Resource Allocation: Two Sides of the Same Coin, 12 BMJ Open e063436 (2022).