Spermatogenesis and the Evolution of Mammalian Sex Chromosomes
Publication Date
8-1-2018
Document Type
Article
Organizational Units
College of Natural Science and Mathematics, Biological Sciences
Keywords
Genomic conflict, Sex-biased expression, Faster-X, Recombination, Hybrid male sterility, Speciation
Abstract
Developmental constraint and sexual conflict shape the evolution of heteromorphic sex chromosomes. These contrasting forces are perhaps strongest during spermatogenesis in species with XY males. In this review, we consider how the unique regulatory environment and selective pressures of spermatogenesis interact to impact sex chromosome evolution in mammals. We explore how each developmental phase of spermatogenesis influences sex chromosome gene content, structure, and rate of molecular evolution, and how these attributes may contribute to speciation. We argue that a developmental context is fundamental to understanding sex chromosome evolution and that an evolutionary perspective can shed new light on our understanding of sperm development.
Copyright Date
8-1-2018
Copyright Statement / License for Reuse
All Rights Reserved.
Rights Holder
Elsevier Ltd.
Provenance
Received from author
Language
English (eng)
Extent
11 pgs
Publication Statement
Copyright is held by Elsevier Ltd. User is responsible for all copyright compliance.
Publication Title
Trends in Genetics
Volume
34
Issue
9
First Page
722
Last Page
732
ISSN
1362-4555
Recommended Citation
Larson, E. L., Kopania, E. E. K., & Good, J. M. (2018). Spermatogenesis and the evolution of mammalian sex chromosomes. Trends in Genetics, 34(9), 722–732. DOI: 10.1016/j.tig.2018.06.003