Date of Award

8-1-2009

Document Type

Dissertation

Degree Name

Ph.D.

Organizational Unit

Morgridge College of Education

First Advisor

Cynthia A. McRae, Ph.D.

Second Advisor

Kathy Green

Third Advisor

Brian D. Hoyt

Fourth Advisor

Roger E. Salters

Keywords

Behavioral medicine, Deep brain stimulation, Movement disorders, Parkinson Disease, Psychology, Quality of life

Abstract

Quality of Life (QOL) in Parkinson's disease (PD) patients after Deep Brain Stimulation (DBS) neurosurgery generally improves between 3 to 24 months post-operatively. However, QOL beyond 2 year follow-up is generally unknown. This study examined the QOL in 16 advanced PD patients who received DBS at an average of 7.5 year follow-up with the Parkinson's Disease Questionnaire (PDQ-39). Participants had an average Disease Duration of 20.57 years (SD 5.7) and a mean Age of 63.50 (SD 8.05). Linear regression analyses suggested a constellation of changes involving Time, Age, and Disease Duration. As Time progressed since DBS intervention, the PDQ-39 Cognitions subscale worsened (p < .05). Increasing Age was associated with improvement in Stigma-related QOL (p < .01). Rising Disease Duration correlated with improvements in three PDQ-39 subscales: (a) Stigma (p < .01), (b) Emotional Well-Being (p < .01), and (c) Social Support (p < .05). Findings suggested the need to further explore the domains and dimensions of QOL change post-DBS intervention, as well as other methods to measure the depth and breadth of QOL in DBS recipients.

Publication Statement

Copyright is held by the author. User is responsible for all copyright compliance.

Rights Holder

Karl S. Chiang

Provenance

Received from ProQuest

File Format

application/pdf

Language

en

File Size

171 p.

Discipline

Clinical psychology, Mental health, Behavioral sciences

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