Passive Liquid Draw Using Micro Needles
Date of Award
6-2015
Document Type
Masters Thesis
Degree Name
M.S.
Organizational Unit
Daniel Felix Ritchie School of Engineering and Computer Science, Mechanical and Materials Engineering
First Advisor
Corinne Lengsfeld
Keywords
Blood test, Needle design, Hypodermic needles
Abstract
The blood draw portion of an in-home blood testing system was investigated with focus on ease of use, pain reduction, flow rate, and the total volume of blood drawn. Traditional style stainless steel hypodermic needles were used in order to investigate the effects of size, viscosity, surface tension, the presence of a porous medium, clogging by tissue, and surface coatings on flow rate through needles in the presence of simulated human capillary bed blood pressure. Non-coring point style needles were found to operate the best in terms of resistance to clogging. Surface effects were found in as large as 26 gauge (0.464 mm OD) needles at low pressure, and were prominent in 31 gauge (0.261 mm OD) and 33 gauge (0.210 mm OD) needles at high pressure. An array of 4-6 needles was conceived to enhance system reliability in light of complicating factors such as viscosity, random obstruction by porous medium, and surface tension.
Publication Statement
Copyright is held by the author. Permanently suppressed.
Rights Holder
Nathan M. Huber
Provenance
Received from author
File Format
application/pdf
Language
en
File Size
89 pgs
Recommended Citation
Huber, Nathan M., "Passive Liquid Draw Using Micro Needles" (2015). Electronic Theses and Dissertations. 2188.
https://digitalcommons.du.edu/etd/2188
Copyright date
2015
Discipline
Engineering