Passive Liquid Draw Using Micro Needles

Date of Award

6-2015

Document Type

Masters Thesis

Degree Name

M.S.

Organizational Unit

Daniel Felix Ritchie School of Engineering and Computer Science, Mechanical and Materials Engineering

First Advisor

Corinne Lengsfeld

Keywords

Blood test, Needle design, Hypodermic needles

Abstract

The blood draw portion of an in-home blood testing system was investigated with focus on ease of use, pain reduction, flow rate, and the total volume of blood drawn. Traditional style stainless steel hypodermic needles were used in order to investigate the effects of size, viscosity, surface tension, the presence of a porous medium, clogging by tissue, and surface coatings on flow rate through needles in the presence of simulated human capillary bed blood pressure. Non-coring point style needles were found to operate the best in terms of resistance to clogging. Surface effects were found in as large as 26 gauge (0.464 mm OD) needles at low pressure, and were prominent in 31 gauge (0.261 mm OD) and 33 gauge (0.210 mm OD) needles at high pressure. An array of 4-6 needles was conceived to enhance system reliability in light of complicating factors such as viscosity, random obstruction by porous medium, and surface tension.

Publication Statement

Copyright is held by the author. Permanently suppressed.

Rights Holder

Nathan M. Huber

Provenance

Received from author

File Format

application/pdf

Language

en

File Size

89 pgs

Discipline

Engineering

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