Association Between Initial Age of Exposure to Childhood Abuse and Cognitive Control: Preliminary Evidence

Publication Date

6-2018

Document Type

Article

Organizational Units

College of Arts Humanities and Social Sciences, Psychology

Keywords

Childhood abuse, Cognitive control, Age, Functional magnetic resonance imaging (fMRI)

Abstract

Cognitive control, which relies on the protracted development of frontal‐parietal regions into adolescence, is a brain process that may be particularly vulnerable to the impact of childhood abuse. In this study, we used functional magnetic resonance imaging (fMRI) to examine associations between the age of onset of childhood abuse and alterations to the neural mechanisms supporting cognitive control in early adulthood, which have not been previously examined. During fMRI scanning, participants completed hybrid block/event‐related versions of a classic color‐word Stroop task as well as emotional Stroop tasks (threat and positive words). Participants were young adult women (N = 15; age range: 23–30 years) who had a history of childhood physical or sexual abuse that began prior to 13 years of age. Results indicated that earlier age of onset of childhood abuse was robustly associated with increased transient (i.e., event‐related) recruitment of medial cognitive control regions in the classic color‐word paradigm as well as with less suppression of medial frontal regions that are part of the default mode network, βs = −.16 to −.87. In comparison, increased activation in dorsolateral prefrontal regions was associated with earlier age of abuse onset under conditions of sustained (i.e., blocked) cognitive control in the emotional Stroop task for blocks of positive distracting words versus fixation, βs = −.50 to −.60. These results provide preliminary evidence that earlier age of exposure to childhood abuse impacts the functional activation of neural systems involved in cognitive control in adulthood.

Copyright Date

5-22-2018

Copyright Statement / License for Reuse

All Rights Reserved
All Rights Reserved.

Publication Statement

Copyright is held by International Society for Traumatic Stress Studies. User is responsible for all copyright compliance. This article was originally published as:

Mackiewicz Seghete, K. L., DePrince, A. P., & Banich, M. T. (2018). Association between initial age of exposure to childhood abuse and cognitive control: Preliminary evidence. Journal of Traumatic Stress, 31(3), 437-447. https://doi.org/10.1002/jts.22290

Accepted Manuscript is openly available through the "Link to Full Text" button.

The published Version of Record is available at libraries through Compass or Worldcat.

Rights Holder

International Society for Traumatic Stress Studies

Provenance

Received from CHORUS

Language

English (eng)

Publication Title

Journal of Traumatic Stress

Volume

31

Issue

3

First Page

437

Last Page

447

ISSN

1573-6598

PubMed ID

29786892

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