Prenatal Maternal Stress, Child Cortical Thickness, and Adolescent Depressive Symptoms
Publication Date
3-6-2020
Document Type
Article
Organizational Units
College of Arts Humanities and Social Sciences, Psychology
Keywords
Prenatal maternal stress, Depressive symptoms, Youth, Pregnancy, Cortical thickness
Abstract
Prenatal maternal stress predicts subsequent elevations in youth depressive symptoms, but the neural processes associated with these links are unclear. This study evaluated whether prenatal maternal stress is associated with child brain development, and adolescent depressive symptoms using a prospective design with 74 mother child pairs (40 boys). Maternal stress was assessed during pregnancy, child cortical thickness at age 7, and depressive symptoms at age 12. Prenatal maternal stress was associated with less cortical thickness primarily in frontal and temporal regions and with elevated depressive symptoms; child cortical thickness additionally correlated with adolescent depressive symptoms. The observed associations are consistent with the possibility that cortical thickness in superior frontal regions links associations between prenatal maternal stress and adolescent depressive symptoms.
Copyright Date
5-9-2019
Copyright Statement / License for Reuse
All Rights Reserved.
Rights Holder
Society for Research in Child Development
Provenance
Received from CHORUS
Language
English (eng)
Publication Statement
Copyright is held by the Society for Research in Child Development. User is responsible for all copyright compliance. This article was originally published as:
Poggi Davis, E., Hankin, B. L., Glynn, L. M., Head, K., Kim, D. J., & Sandman, C. A. (2020). Prenatal maternal stress, child cortical thickness, and adolescent depressive symptoms. Child Development, 91(2), e432-e450. https://doi.org/10.1111/cdev.13252
Publication Title
Child Development
Volume
91(2)
First Page
e432
Last Page
e450
ISSN
1467-8624
PubMed ID
31073997
Recommended Citation
Poggi Davis, E., Hankin, B. L., Glynn, L. M., Head, K., Kim, D. J., & Sandman, C. A. (2020). Prenatal maternal stress, child cortical thickness, and adolescent depressive symptoms. Child Development, 91(2), e432-e450. https://doi.org/10.1111/cdev.13252